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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6640ed60c501203d504bda08722c59124136fe166785d04fcf622fb5ae3b1262' 
  AND token = 'MWOCZzG/Ts69Cu52m/Os+ngK91tx7OePOTqMI/0ghp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}