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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb7243ce598d3473e5bfb379c48d517894544acdc21a0a3ff2a3345f4f39346e' 
  AND token = 'FU3hmt8hGPkLwUE7Rn4Ic8lxv63/dQsmbBNlUlTXaR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}