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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b5bfe16be4072ef4e02c8684704895fcce2292224e7fc708a52fa783bb1b729' 
  AND token = 'XxpI2ATy7URsfFzGUOrLzlq5rDXxtn/CGscrjX7pGhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}