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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '077e2154cb1c2d60834f969948ac674596c7750cd48896f12ed1833aa62c4751' 
  AND token = 'NHK7T/aomg2TqjPaNhVa4nVUVHWitzN4ntWZdzjKFag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}