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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c42997b4c9cafbc7a9d63c552de3a2c2bb4ace98c33b4aa300e5b623bba052c5' 
  AND token = '/zb9yYKuFxZOTOP0EnNQ4ohRb93L5HAAqTXplSJg2pM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}