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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e33c8952d262e19003adaa4a3595a7e1c279f7b38a2d760c94a689d7ae48f8bb' 
  AND token = '66+wFCKyIxMeQYfrMVfhCG32Vl1x5heelfQ/z8PpKI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}