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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f49404468e788546b4151aa177fd1fc3b4b72fb5994c722e4a0821b97923c66b' 
  AND token = 'Z89mf2VQQEe2qtHTAIAgnSgDjEHG6LmpUI+ccrXby6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}