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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dbc7b26e0636adc51de9a8da67b21e106148ec2bcab6068c39d50f0085d7c20' 
  AND token = 'nONpsTuOT8j4UDJBx+a5gqveFHBjtVLG/A5qm+pN3l8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}