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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15fa8a46bcf70fdcc99537fcc6181560b4cc9e33dd5f3fefb1d6f2e84cf740f6' 
  AND token = '7ipuK5nwtkbdKvyNgz16+xwBwo5Uoz0i2sgpkw2iOxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}