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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a5fd6805a7bff5840da11ea753ca0c27a5e884bf9f1c7d392be98b176dfc815' 
  AND token = 'PPy0ZXwjZ69WBdhroEwCyO869COiUpAewp0ZQ1AEVZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}