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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a8d2d03e7e3cfdb444da2a58a1f2ce6800307f95ad19f50789242c15b113d96' 
  AND token = 'WNPYCu1UCEWQBZkgQIKmW+xQ+786hlbzTmriN1rRhO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}