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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a43d8a6b838e738875a52f5f82a58f7caeec3cbef6238577f9df23d7dd48612' 
  AND token = 'OS62AQA1/Pni49BfYObdakYVTxkiC1nhbU9X4EIQyts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}