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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5729e16b3098296df0c6896bc158c857f876c7cc21d322f81318d0ce9f2bbdd' 
  AND token = 'HlSjDT/e+E8OsMJf7BJPHMHOwmEyNABPhvQjmiq1j7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}