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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fb1e6c3426a0d6379ffe3c55e9a3a1d5e0d7eee213abedd9d06126094c63087' 
  AND token = 'vJWVLqL5mgYKHOKqPN2jcu3RV45QwUxXl9Nwiq2u1Mo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}