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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '105b817b1403c4ea29c67b159753e9855b68be65ebb346bd0a9acdbe7bae50c5' 
  AND token = 'JDEb5EIB16lx6f2OPR95qjLPlOcBmncGf/rRr9+4a5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}