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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a650df91bc08b23cb74f8e12f9f284acaa54eb1eac15a643c35d4ef55a3e1330' 
  AND token = 'Vk6sCPcy496gOPXsN9PfPZmNBa8WUQZVSgHYPWpQWcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}