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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b483aed04b0ff0ed62744a96f0e558c49c0ad83267404e453be7348a323727d' 
  AND token = 'HGOUfZPkpNtSosWx7bkFpl1SKEQLKcRcb6hokbb+r8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}