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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e8f4d4b0570adf983cf080514f50c16e4016356950822e8d24ee6b12dccf594' 
  AND token = 'uPXAP1mwVfjURG7DwN2h1zVbziNMmbsint4966B9pIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}