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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f21074c1c2e522d0e4e84772ce9762b08c012771b012f882918f447e79c1348' 
  AND token = '8qBSyu0p2oiq47P3lwgdkB0UzezEpsKMf4vqrHNgd+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}