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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8ff0e179b941f66851a58a149bace32d20bb80ecb6df75fb9babb26383ab6cb' 
  AND token = 'jy7vsyqM9DrrcCN7Qz4JK1yrK37ARGP4IAuBfxbQtwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}