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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65032a4298bbcbb7630a4b8e96013b2b4aa4ed5e55a77eadb4126317e707d19c' 
  AND token = 'rBHwKaUhEahHncOfhVSCdGweN6uqPk+Z+78KH1IDhec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}