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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b57eb98d21752ba6444d9df50d3a741cf9e8bd2f0fa0033ff55170c9f5832842' 
  AND token = 'LeRrhlapL7x3f8Yo2KfGL2B6fCAIPmYqAMn89AlkOHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}