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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46d03f9e22b70b89ed765ca4c4b76ccf1e07b5201d9a82bdc48bb395b9334560' 
  AND token = 'D65QRJ40uk0AOsgfRatYtc81/BoRuyvcK/0VjM8eTLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}