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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ecf4e047d967052c37b5c6344c8281140c5d2c5f602a07661d5c3789506712c' 
  AND token = 'RBo+o9n8HSXZhMnhSzBDsSysEnQLmQGQjlxRp9ulQ2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}