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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '923c8d0f871491165e79bc99ab26fc9624947515f1fe4e5099fbc49e8e92480a' 
  AND token = 'jWOSZuIEMxUE/StQMwpDAvtLC/WkF65aEi9D3NqsHPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}