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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a195e2a034f8f5c1935e9e6cf644a5c6fde77afd8a4cb0341e73d526dec5b647' 
  AND token = 'IIYqA3VbCjNxlZvQWYlkxEzKduIcOBp5KY7C3zb+tdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}