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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2f810e02d5c02874633e7dc5b6f8fad0bacc453b1cde4f8e8c724f802193012' 
  AND token = 'aOanNwq7cPLqUdimKi+giQ6UFRrfvOOcHVCTVE7UIog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}