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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e80b6c787fed94ea3b704df8ae2d8f0cd4c54562246224c27d50aab9c23c324' 
  AND token = 'bPC+ZWp/lr1s/yRie+todPsFMEqLpWyHpej9dmW3vZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}