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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f049d5dbe997aa54c54f656bacb9c8430dca13dfb70e6e1b75701b87f961fe72' 
  AND token = 'PiJec4SZj7a9f3yQZ4bytbWuXCv/L2Tfs+qbvFLjfQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}