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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82499250db6f023101f432c4b2d57e2388a259c2926ce09a02395edd6ce9b5ed' 
  AND token = '1ZRuKiGAZ94mPyMhmyEmK91L9xMjhzEPvc+v+woBJuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}