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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea18616e19c506e26165d86e4ab70f64dbd1782714bfba12ae608eeb21a6e25c' 
  AND token = 'OrIsL0oEY94AVUKDQeMoYPNFsgyWDddpjE3LllAu9YY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}