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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee3a9c19fd3f29c3b65fd0798996659affa24ec20d4963bd7b327efe14927c9a' 
  AND token = 'B2C6ovXJsd0e6GSgFzpRB0jXfvP34ISqYn0kB3aRVek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}