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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1eec0fc8869131cf45347dd6afb4c89a98b2b3ee169ac8a8846f2c38c8703431' 
  AND token = 'zdoXr46qxIFePOHSlTLBjcnekiMOTgvsGilCXvvJ2RM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}