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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17c4c575cee8a3ec7c2dfd16653cf94d30f1f88e213855038d01c2080c9f8fea' 
  AND token = 'UrLp/sMKQ1uzEb0oC/aL/73tLXdestbV7IQS3uIjDi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}