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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd17c17e565b0c1342c0f5aa3646279647fc427fe1c318e04caaf32163e22bbbc' 
  AND token = 'ay4ONoP6XgK6gDwDLYseowUh9OoxLQDCxxf2OvGcbS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}