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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3bbecfb86b5ed65365c2a7fce7abd932ef1e2b99545f6fe7888050299ee9178' 
  AND token = 'FZ/KNEQ3eQWNPhYeriCTiCa0diFX4FHoXMuBY4c451Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}