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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e9b6f3f18588011bba76cfd3c46c45aaef4c36dbdc53a176d21b1d401b14933' 
  AND token = 'CX6XuZp0E9sIw49x4GKuOo4bGBFtFGiPdQ3B12qEbqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}