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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e6c79f50f336658a75933478a6602c8b87ac911a8763b0054451e3010d90912' 
  AND token = 'cuMY0PNA4R6MCIlG0ay84ZA+takyVWhwVq55ZY58VBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}