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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5296fb37108ccb28696379093606eea9faed6ea09b313c9db74c32127a727eb8' 
  AND token = '+9nZC1gZCnTZDpWXfBe4GZ4xuXkmnIfy3QH3w7jc3aY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}