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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f43c5d307135f48e277795f06fdaef086b6159a73429f1b3e6f5d4169fabd461' 
  AND token = 's8y94zwJ7syaPM8nIj0e/IhhoeRqxTYEPC5TQr4duV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}