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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3346bce3d80e81ce006dbdd8645331cf174fa7d9da818e2a6af19d2ee1cd652' 
  AND token = 'Gj7DOY+m/ZJydjqtrL1OpjSpC4uPpznP44gdwb10vH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}