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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd21283af8dfa8cdbf5f9e86d6e3887d5fccd7f7f63ef6ce79d2249c295b403a6' 
  AND token = 'ZX65CWjpMtfbFxotm74V9b3n10hmipyowj9LT1H8DEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}