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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72e5b382d9d55f67c1bb32abd5002ef285b2e71c816515a86f9d23aba3de31a0' 
  AND token = 'vGQkvckTzit+c9DndOCkct4f1c1fwDg6vR7iWwKeADs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}