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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1cf3e1791c12fc37b18d0c94eaf0a3ca7969a1efcea43534a5e479291bc3856' 
  AND token = 'qXq6h5nkAcmhlVdSY9aCza3zZMoEKZP1kexEXBwVg3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}