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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d99d532d872cedd3e4fa49dd5c91512671b737edabd8fc5e19107387894fbcd' 
  AND token = 'HXgD2NfYmg9/Xxtz7LgMT4gSN1waVuznxSmXR2/A8iU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}