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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '557d67106e33d13c3127a404ed6d0ad04033246f81507eabe0718b15dda7d5e9' 
  AND token = 'MU/kDv/p8lEH8iFfFF4h8RH1pActiG5ULMQs/+nKCe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}