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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2fc28629bfa441e707d8d65a489f4710d6c7d7c408341e14bfc654937900b8f' 
  AND token = 'yUU5ijlV/JtfOMXJcwcbIHs/pMMN4M+eWBBL+PLVlFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}