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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81d06b3201b7230553701e1bf81fb052c9c5100273f8385460795e881744dd5a' 
  AND token = 'HSQW3dZzs20JE6nrLXQpgm+EjitECx5xhau7B7iqLYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}