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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8177f5541cd22d3c387eb921cac2bee8d1065d1110bc438c738ed06cbc3a90bb' 
  AND token = '9wgRKtznDynGGhIpGTVNa16G757vtAk8P2LIAimrIWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}