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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '648862371b84054433aaa9fc8b3976e69f76ff71b6b8de164de406b4e90c0a13' 
  AND token = '0AurWrgU2vACLibdR7jDODQSh1xIkWfG7EXMYsqV5aQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}